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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Finerenone ： ウィキペディア英語版 Finerenone Finerenone (INN, USAN) is a nonsteroidal antimineralocorticoid that is in Phase III clinical trials for the treatment of chronic heart failure . It has less relative affinity to other steroid hormone receptors than currently available antimineralocorticoids such as eplerenone and spironolactone, which should result in fewer adverse effects like gynaecomastia, impotence, and low sex drive.〔Schubert-Zsilavecz, M, Wurglics, M, ''Neue Arzneimittel Herbst 2015'' 〕 ==Pharmacology== Finerenone blocks mineralocorticoid receptors, which makes it a potassium sparing diuretic. This table compares inhibitory (blocking) concentrations (IC50, unit: nM) of three antimineralocorticoids. Mineralocorticoid receptor inhibition is responsible for the desired action of the drugs, whereas inhibition of the other receptors potentially leads to side effects. Lower values mean stronger inhibition.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Finerenone」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.