翻訳と辞書 Words near each other ・ (+)-epicubenol synthase ・ (+)-gamma-cadinene synthase ・ (+)-germacrene D synthase ・ (+)-Larreatricin hydroxylase ・ (+)-Menthofuran synthase ・ (+)-Naloxone ・ (+)-neomenthol dehydrogenase ・ (+)-Pulegone reductase ・ (+)-Sabinene 3-hydroxylase ・ (+)-sabinene synthase ・ (+)-sabinol dehydrogenase ・ (+)-sativene synthase ・ (+)-T-muurolol synthase ・ (+)-Thujan-3-ol dehydrogenase ・ (+)-trans-carveol dehydrogenase ・ (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane ・ (-)-2β-(3-(4-Methylphenyl)isoxazol-5-yl)-3β-(4-chlorophenyl)tropane ・ (-)-alpha-cuprenene synthase ・ (-)-alpha-pinene synthase ・ (-)-alpha-terpineol synthase ・ (-)-beta-caryophyllene synthase ・ (-)-beta-pinene synthase ・ (-)-borneol dehydrogenase ・ (-)-camphene synthase ・ (-)-delta-cadinene synthase ・ (-)-endo-alpha-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) ・ (-)-Endo-fenchol dehydrogenase ・ (-)-endo-fenchol synthase ・ (-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing) ・ (-)-germacrene D synthase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane ： ウィキペディア英語版 (-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane RTI-126 ((–)-2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane) is a phenyltropane derivative which acts as a potent monoamine reuptake inhibitor and stimulant drug. It is around 5 times more potent a stimulant than cocaine, but is relatively unselective. It binds to all three monoamine transporters, although still with some selectivity for the dopamine transporter. RTI-126 has a fast onset of effects and short duration of action, and its pharmacological profile in animals is among the closest to cocaine itself out of all the drugs in the RTI series. Its main application in scientific research has been in studies investigating the influence of pharmacokinetics on the abuse potential of stimulant drugs, with its rapid entry into the brain thought to be a key factor in producing its high propensity for development of dependence in animals. The structurally related compound (–)-2β-(3-methyl-5-isoxazolyl)nortropane is a potent and selective agonist for nicotinic acetylcholine receptors, with twice the potency of nicotine.〔Cheng J, Izenwasser S, Zhang C, Zhang S, Wade D, Trudell ML. Synthesis and nicotinic acetylcholine receptor binding affinities of 2- and 3-isoxazolyl-8-azabicyclo()octanes. ''Bioorganic and Medicinal Chemistry Letters''. April 2004; 14(7):1775-1778. PMID 15026069〕 == See also == * List of cocaine analogues 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「(-)-2β-(1,2,4-Oxadiazol-5-methyl)-3β-phenyltropane」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.