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| Section2 = }} 1,4,7-Triazacyclononane, known as "TACN" which is pronounced "tack-en," is a cyclic organic compound with the formula C6H12(NH)3.〔Chaudhuri, P. and Wieghardt, K., "The Chemistry of 1,4,7-Triazacyclononane and Related Tridentate Macrocyclic Compounds", ''Progress in Inorganic Chemistry'', 1987, volume 35, 329-436〕 TACN is derived, formally speaking, from cyclononane by replacing three equidistant CH2 groups with NH groups. TACN is one of the oligomers derived from aziridine, C2H4NH. Other members of the series include piperazine, C4H8(NH)2, and the cyclic tetramer 1,4,7,10-tetraazacyclododecane. ==Synthesis== The ligand is prepared from diethylene triamine as follows by macrocyclization using ethyleneglycol ditosylate.〔K. Wieghardt, W. Schmidt, B. Nuber, and J. Weiss, "Darstellung und Struktur des trans-Diaqua-di-μ-hydroxo-bis()-Kations; Kinetik und Mechanismus seiner Bildung"''Chem. Ber.'', 1979, 112, 2220-2230.〕 :H2NCH2CH2NHCH2CH2NH2 + 3 TsCl → Ts(H)NCH2CH2N(Ts)CH2CHH2N(H)Ts + 3 HCl :Ts(H)NCH2CH2N(Ts)CH2CH2N(H)Ts + 2 NaOEt → Ts(Na)NCH2CH2N(Ts)CH2CH2N(Na)Ts :Ts(Na)NCHH2CH2N(Ts)CH2CH2N(Na)Ts + TsOCH2CH2OTs + → ()3 + 2 NaOTs :()3 + 3 H2O → ()3 + 3 HOTs 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「1,4,7-Triazacyclononane」の詳細全文を読む スポンサード リンク
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