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11β,21-Dihydroprogesterone : ウィキペディア英語版
Corticosterone

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Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands in rodents and other non-human animals.
==Roles==
In many species, including amphibians, reptiles, rodents and birds, corticosterone is a main glucocorticoid,〔(【引用サイトリンク】title=e.hormone | The Hormones : Corticoids )〕 involved in regulation of energy, immune reactions, and stress responses.
However, in humans, corticosterone is the primary glucocorticoid that is produced primarily in the zona fasciculata of the adrenal cortex. It has only weak glucocorticoid and mineralocorticoid potencies in humans and is important mainly as an intermediate in the steroidogenic pathway from pregnenolone to aldosterone. Corticosterone is converted to aldosterone by aldosterone synthase, found only in the mitochondria of glomerulosa cells. Glomerulosa cells are found in the Zona glomerulosa, which is the most superficial region of endocrine cells in the adrenal cortex.
Corticosterone is the precursor molecule to the mineralocorticoid aldosterone, one of the major homeostatic modulators of sodium and potassium levels in vivo.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Corticosterone」の詳細全文を読む



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