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・ 141st (5th London) Brigade
・ 141st (Rainy River District) Battalion (Border Bull Moose), CEF
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・ 14"/50 caliber railway gun
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14-Cinnamoyloxycodeinone
・ 14-Ethoxymetopon
・ 14-Hydroxydihydrocodeine
・ 14-inch gun M1907
・ 14-inch M1920 railway gun
・ 14-methoxydihydromorphinone
・ 14-Methoxymetopon
・ 14-Norpseurotin A
・ 14-Phenylpropoxymetopon
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・ 14.5mm JDJ
・ 14.5×114mm
・ 14/48
・ 140
・ 140 (number)


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14-Cinnamoyloxycodeinone : ウィキペディア英語版
14-Cinnamoyloxycodeinone

14-Cinnamoyloxycodeinone is the most potent example in a series of opiate analgesic drugs discovered in the 1960s, with > ×100 times the potency of morphine. It is a derivative of , being the 14-cinnamate ester. In another paper, Buckett assigns the potency as 177 with a range (depending on animal and test) of ×101 - ×310.〔'The relationship between analgesic activity, acute toxicity and chemical structure in esters of 14-hydroxycodeinone' W.R.Buckett J. Pharm. Pharmacol., 1964, 16, Suppl., 68T-71T〕 It may be of interest to researchers that the allyl group in this compound and in allylprodine overlay very closely.
==See also==

* 14-Phenylpropoxymetopon
* 7-PET
* N-Phenethylnormorphine
* N-Phenethyl-14-ethoxymetopon
* Phenomorphan
* RAM-378
* Ro4-1539

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「14-Cinnamoyloxycodeinone」の詳細全文を読む



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