| 翻訳と辞書 |
| 16-Methoxytabersonine ： ウィキペディア英語版 |
16-Methoxytabersonine
16-Methoxytabersonine is a terpene indole alkaloid produced by the medicinal plant ''Catharanthus roseus''. 16-methoxytabersonine is synthesized by methylation of the hydroxyl group at the 16 position of 16-hydroxytabersonine by tabersonine 16-O-methyltransferase (16OMT).〔Levac, Murata, Kim and De Luca (2008) Application of carborundum abrasion for investigating the leaf epidermis: molecular cloning of Catharanthus roseus 16-hydroxytabersonine-16-O-methyltransferase. The Plant Journal. 53(2). 225-236〕 The compound is a substrate for hydration by two concerted enzymes Tabersonine-3-Oxidase (T3O) and Tabersonine-3-Reductase (T3R), which leads to the formation of 3-hydroxy-16-methoxy-2,3-dihydrotabersonine.〔Qu, Y., Easson, M. L., Froese, J., Simionescu, R., Hudlicky, T., & De Luca, V. (2015). Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast. Proceedings of the National Academy of Sciences, 112(19), 6224-6229.〕
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「16-Methoxytabersonine」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|