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|Section2= |Section3= }} 2,6-Di-''tert''-butylpyridine is an organic compound with the formula (Me3C)2C5H3N. This colourless, oily liquid is derived from pyridine by replacement of the two H atoms with tert-butyl groups. It is a hindered base.〔Rafael R. Kostikov, Sánchez-Sancho Francisco, María Garranzo and M. Carmen Murcia "2,6-Di-t-butylpyridine" Encyclopedia of Reagents for Organic Synthesis 2010. 〕 For example, it can be protonated, but it does not form an adduct with boron trifluoride. ==Preparation== 2,6-Di-''tert''-butylpyridine is prepared by the reaction of tert-butyllithium with pyridine.〔Edward Deutsch, Nai Kong V. Cheung "Noncoordinating buffers. I. Synthesis and characterization of water soluble derivatives of 2,6-di-tert-butylpyridine" ''J. Org. Chem'' 1973, vol 38, pp 1123–1126. 〕 The synthesis is reminiscent of the Chichibabin reaction. Some related bulky pyridine compounds have been described, including 2,4,6-tri-t-butylpyridine.〔Francis V. Scalzi, Norman F. Golob "Alkylation of pyridine with tert-butyllithium. Convenient syntheses of 2,6-di-tert-butylpyridine and 2,4,6-tri-tert-butylpyridine" ''J. Org. Chem'' 1971, vol 36, pp 2541–2542 . Hongmei Li "2,4,6-Tri-tert-butylpyridine" Encyclopedia of Reagents for Organic Synthesis 2004. 〕 and 2,6-di-tert-butyl-4-methylpyridine.〔Alexandru T. Balaban "2,6-Di-tert-butyl-4-methylpyridine (DTBMP)" Encyclopedia of Reagents for Organic Synthesis 2004. 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「2,6-Di-tert-butylpyridine」の詳細全文を読む スポンサード リンク
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