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2-Benzylpiperidine : ウィキペディア英語版 | 2-Benzylpiperidine
2-Benzylpiperidine is a stimulant drug of the piperidine class. It is similar in structure to other drugs such as methylphenidate and desoxypipradrol but around 20 times less potent, and while it boosts norepinephrine levels to around the same extent as d-amphetamine, it has very little effect on dopamine levels, with its binding affinity for the dopamine transporter around 175 times lower than for the noradrenaline transporter. 2-benzylpiperidine is little used as a stimulant, with its main use being as a synthetic intermediate in the manufacture of other drugs.〔Ágai B, Proszenyák A, Tárkányi G, Vida L, Faigl F. Convenient, Benign and Scalable Synthesis of 2- and 4-Substituted Benzylpiperidines. ''European Journal of Organic Chemistry'' 2004; 17:3623-3632. 〕〔(Christopher F. Bigge, John F. W. Keana, Sui Xiong Cai, Eckard Weber, Richard Woodward, Nancy C. Lan, Anthony P. Guzikowski. 2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists. US Patent 6124317 )〕 == See also ==
* 4-Benzylpiperidine * Benzylpiperazine
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