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|Section2= |Section3= }} Phenylethanolamine (sometimes abbreviated PEOH), or β-hydroxyphenethylamine, is a trace amine with a structure similar to those of other trace phenethylamines as well as the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine. As an organic compound, phenylethanolamine is a β-hydroxylated phenethylamine that is also structurally related to a number of synthetic drugs in the substituted phenethylamine class. In common with these compounds, phenylethanolamine has strong cardiovascular activity〔W. H. Hartung (1945). "Beta-phenethylamine derivatives." ''Ind. Eng. Chem.'' 37 126–136.〕 and, under the name ''Apophedrin'', has been used as a drug to produce topical vasoconstriction.〔''The Merck Index, 10th Ed.'' (1983), p. 1051, Merck & Co., Rahway.〕 In appearance, phenylethanolamine is a white solid. Phenylethanolamine is perhaps best known in the field of bioscience as part of the enzyme name "phenylethanolamine N-methyl transferase", referring to an enzyme which is responsible for the conversion of norepinephrine into epinephrine, as well as other related transformations.〔J. Axelrod (1966). "Methylation reactions in the formation and metabolism of catecholamines and other biogenic amines. ''Pharmacol. Rev.'' 18 95–113.〕 ==Occurrence== Phenylethanolamine has been found to occur naturally in several animal species, including humans.〔E. E. Inwang, A. D. Mosnaim and H. C. Sabelli (1973). "Isolation and characterization of phenethylamine and phenylethanolamine from human brain." ''J. Neurochem.'' 20 1469–1473.〕〔H. E. Shannon and C. M. Degregorio (1982). "Self-administration of the endogenous trace amines beta-phenylethylamine, N-methyl phenylethylamine and phenylethanolamine in dogs." ''J. Pharmacol. Exp. Ther.'' 222 52–60.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Phenylethanolamine」の詳細全文を読む スポンサード リンク
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