|
|Section2= |Section3= |Section4= |Section5= |Section6= |Section7= |Section8= }} Coenzyme M is a coenzyme required for methyl-transfer reactions in the metabolism of methanogens. The coenzyme is an anion with the formula . It is named 2-mercaptoethanesulfonate and abbreviated HS–CoM. The cation is unimportant, but the sodium salt is most available. Mercaptoethanesulfonate contains both a thiol, which is the main site of reactivity, and a sulfonate group, which confers solubility in aqueous media. == Biochemical role == The coenzyme is the C1 donor in methanogenesis. It is converted to propyl coenzyme M-thioester, the thioether , in the penultimate step to methane formation. Coenzyme M reacts with coenzyme B, 7-thioheptanoylthreoninephosphate, to give a homodisulfide, releasing methane: : + HS–CoB → + CoB–S–S–CoM This induction is catalyzed by the enzyme methyl-coenzyme M reductase, which restricts cofactor F430 as the prosthetic group. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Coenzyme M」の詳細全文を読む スポンサード リンク
|