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21-Hydroxylase
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21-Hydroxylase : ウィキペディア英語版
21-Hydroxylase

Steroid 21-hydroxylase is a cytochrome P450 enzyme that is involved with the biosynthesis of the steroid hormones aldosterone and cortisol.
In humans, 21-Hydroxylase is encoded by the gene ''CYP21A2''.
== Function ==

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1589 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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