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23S : ウィキペディア英語版
23S ribosomal RNA

The 23S rRNA is a 2904 nt long (in ''E. coli'') component of the large subunit (50S) of the bacterial ribosome. The ribosomal peptidyl transferase activity resides in domain V of this rRNA, and this domain is the most common binding site for antibiotics that inhibit translation. A well-known member of this antibiotic class, Chloramphenicol, acts by inhibiting peptide bond formation, with recent 3D-structural studies showing two different binding sites depending on the species of ribosome. Linezolid and quinupristin-dalfopristin also bind to the 23S rRNA, and cross-resistance has been demonstrated between these antibiotics.
==See also==

*23S methyl RNA motif

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「23S ribosomal RNA」の詳細全文を読む



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