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・ 2C-B-BZP
・ 2C-B-FLY
・ 2C-C
・ 2C-D
・ 2C-E
・ 2C-F
・ 2C-G
・ 2C-I
・ 2C-iP
・ 2C-N
・ 2C-O-4
・ 2C-P
・ 2C-T
・ 2C-T-13
・ 2C-T-15
2C-T-16
・ 2C-T-17
・ 2C-T-19
・ 2C-T-2
・ 2C-T-21
・ 2C-T-4
・ 2C-T-7
・ 2C-T-8
・ 2C-TFM
・ 2C-YN
・ 2C2P
・ 2CA
・ 2CB-Ind
・ 2CBCB-NBOMe
・ 2CBFly-NBOMe


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2C-T-16 : ウィキペディア英語版
2C-T-16

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2C-T-16 is a lesser-known psychedelic drug. It was originally named by Alexander Shulgin as described in his book PiHKAL (Phenethylamines i Have Known And Loved), however while Shulgin began synthesis of this compound he only got as far as the nitrostyrene intermediate, and did not complete the final synthetic step. Synthesis of 2C-T-16 was finally achieved by Daniel Trachsel some years later,〔Trachsel D. Synthesis of novel (phenylalkyl)amines for the investigation of structure-activity relationships. Part 2. 4-Thio-substituted ()amines (=2,5-dimethoxybenzeneethanamines). ''Helvetica Chimica Acta''. 2003; 86(7):2610–2619. doi:10.1002/hlca.200390210〕 and it was subsequently reported as showing similar psychedelic activity to related compounds, with a dose range of 10-25mg and a duration of 4-6 hours,〔Daniel Trachsel, David Lehmann and Christoph Enzensperger. Phenethylamine Von der Struktur zur Funktion, pp 788-789. Nachtschatten Verlag AG, 2013. ISBN 978-3-03788-700-4〕 making it around the same potency as the better-known saturated analogue 2C-T-7, but with a significantly shorter duration of action. Binding studies ''in vitro'' showed 2C-T-16 to have a binding affinity of 44nM at 5-HT2A and 15nM at 5-HT2C.〔Ibid., p 791.〕 Some related compounds have been shown to be MAOIs, and this may also be the case for 2C-T-16 in addition to its 5-HT2 agonist effects.
== See also ==

* Phenethylamine
* Psychedelics, dissociatives and deliriants

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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