翻訳と辞書 ・ 3-dehydroquinate synthase II ・ 3-Dehydroquinic acid ・ 3-dehydroshikimate dehydratase ・ 3-Dehydroshikimic acid ・ 3-dehydrosphinganine reductase ・ 3,3',5,5'-Tetramethylbenzidine ・ 3,3',5-Triiodothyronamine ・ 3,3'-Diaminobenzidine ・ 3,3'-Dichlorobenzidine ・ 3,3'-Diindolylmethane ・ 3,3'-Diiodothyronine ・ 3,3,4,4-Tetramethyltetrahydrofuran ・ 3,3,4,4-Tetramethyltetrahydrofuran-2,5-dione ・ 3,3-Bis(chloromethyl)oxetane ・ 3,3-Diethyl-2-pyrrolidinone ・ 3,3-Diphenylcyclobutanamine ・ 3,3-Diphenylpropylamine ・ 3,4,5-Tri-O-galloylquinic acid ・ 3,4,5-Trimethoxybenzaldehyde ・ 3,4,8-Trimethoxyphenanthrene-2,5-diol ・ 3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) ・ 3,4-Diaminopyridine ・ 3,4-Dichloroamphetamine ・ 3,4-dichloroaniline N-malonyltransferase ・ 3,4-Dichlorobicyclo(3.2.1)oct-2-ene ・ 3,4-Dichloromethylphenidate ・ 3,4-Dichlorphenylisocyanate ・ 3,4-dihydroxy-2-butanone-4-phosphate synthase ・ 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase ・ 3,4-Dihydroxymandelic acid
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3,3-Diphenylcyclobutanamine : ウィキペディア英語版 | 3,3-Diphenylcyclobutanamine
3,3,-Diphenylcyclobutanamine is a psychostimulant drug which was originally prepared as an antidepressant in the late 1970s. It appears to inhibit the reuptake of serotonin, norepinephrine, and dopamine, and may also induce their release as well.〔 The ''N''-methyl and ''N'',''N''-dimethyl analogues of the compound are also known and are more potent.〔 All three agents produce locomotor stimulation in animal studies, with the tertiary amine being the strongest.〔 ==Synthesis== A number of methods were tried in order to construct the strained four-carbon ring. A synthesis of 3,3-diphenylcyclobutanone appeared in the literature. The ketone was prepared in low yield by the reaction of diphenylketene with 2 equiv of diazomethane. The latter synthesis, although low yielding, was used and the desired amines were prepared from 3,3-diphenylcyclobutanone.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「3,3-Diphenylcyclobutanamine」の詳細全文を読む
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