翻訳と辞書 ・ 3,3-Diphenylcyclobutanamine ・ 3,3-Diphenylpropylamine ・ 3,4,5-Tri-O-galloylquinic acid ・ 3,4,5-Trimethoxybenzaldehyde ・ 3,4,8-Trimethoxyphenanthrene-2,5-diol ・ 3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) ・ 3,4-Diaminopyridine ・ 3,4-Dichloroamphetamine ・ 3,4-dichloroaniline N-malonyltransferase ・ 3,4-Dichlorobicyclo(3.2.1)oct-2-ene ・ 3,4-Dichloromethylphenidate ・ 3,4-Dichlorphenylisocyanate ・ 3,4-dihydroxy-2-butanone-4-phosphate synthase ・ 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase ・ 3,4-Dihydroxymandelic acid ・ 3,4-Dihydroxyphenylacetaldehyde ・ 3,4-dihydroxyphenylacetate 2,3-dioxygenase ・ 3,4-Dihydroxyphenylacetic acid ・ 3,4-dihydroxyphenylalanine oxidative deaminase ・ 3,4-dihydroxyphenylalanine reductive deaminase ・ 3,4-dihydroxyphthalate decarboxylase ・ 3,4-Dihydroxystyrene ・ 3,4-Dimethoxycinnamic acid ・ 3,4-Dimethoxyphenethylamine ・ 3,4-Dimethoxystyrene ・ 3,4-Dimethylmethcathinone ・ 3,4-Divanillyltetrahydrofuran ・ 3,4-Epoxycyclohexanecarboxylate methyl ester ・ 3,4-Epoxycyclohexylmethyl-3’,4’-epoxycyclohexane carboxylate ・ 3,4-Ethylidenedioxyamphetamine
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3,4-Dihydroxyphenylacetaldehyde : ウィキペディア英語版 | 3,4-Dihydroxyphenylacetaldehyde
|Section2= |Section3= }} 3,4-Dihydroxyphenylacetaldehyde (DOPAL) is a metabolite of the neurotransmitter dopamine. DOPAL is an important precursor of the major brain metabolites of dopamine, 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxy-phenylacetic acid. DOPAL plays a role in Parkinson's disease.〔Goldstein DS, Sullivan P, Holmes C, Miller GW, Alter S, Strong R, Mash DC, Kopin IJ, Sharabi Y., "Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease," J Neurochem. 2013 Sep;126(5):591-603. 〕 DOPAL has been chemically synthesized.〔Li, W., Spaziano, V.T., Burke, WJ., "Synthesis of a biochemicallly important aldehyde - 3,4-dihydroxyphenylacetaldehyde", Bio-Organic Chemistry, 26, 45-50, 1998.〕 == References ==
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