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・ 3-Fluoromethcathinone
・ 3-Fluorophenmetrazine
・ 3-fold
・ 3-fumarylpyruvate hydrolase
・ 3-Fumarylpyruvic acid
・ 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
・ 3-Gun Nation
・ 3-Headed Shark Attack
・ 3-Heptanol
・ 3-Heptanone
・ 3-Hexanol
・ 3-Hexanone
・ 3-hexulose-6-phosphate synthase
・ 3-Hexyne
・ 3-HO-PCP
3-Hydroxy-16-methoxy-2,3-dihydrotabersonine
・ 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
・ 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
・ 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
・ 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
・ 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
・ 3-hydroxy-3-isohexenylglutaryl-CoA lyase
・ 3-hydroxy-3-methylglutaryl-CoA lyase
・ 3-hydroxy-3-methylglutaryl-CoA lyase deficiency
・ 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
・ 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase
・ 3-hydroxy-D-aspartate aldolase
・ 3-Hydroxyacetophenone
・ 3-Hydroxyacyl ACP dehydrase
・ 3-hydroxyacyl-CoA dehydrogenase


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3-Hydroxy-16-methoxy-2,3-dihydrotabersonine : ウィキペディア英語版
3-Hydroxy-16-methoxy-2,3-dihydrotabersonine

3-Hydroxy-16-methoxy-2,3-dihydrotabersonine is a terpene indole alkaloid produced by ''Catharanthus roseus''. The metabolite is a substrate for 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase (NMT) which transfers a methyl group to the nitrogen of the indole ring forming desacetoxyvindoline.〔Dethier and De Luca (1993) Partial purification of an N-methyltransferase involved in vindoline biosynthesis in Catharanthus roseus. Phytochemistry. 32(3). 673-678〕 The enzyme catalyzing the formation of 3-hydroxy-16-methoxy-2,3-dihydrotabersonine from 16-methoxytabersonine is currently unknown, but is a result of hydration of the double bond connecting the 6 and 13 position carbons.〔Liscombe, Usera and O’connor (2010) Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis. Proceedings of the National Academy of Sciences. 107(44). 18793-18798〕 〔O'connor and Maresh (2006) Chemistry and biology of monoterpene indole alkaloid biosynthesis. Natural Product Reports. 23(4). 532-547〕
==References==


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