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・ 3-3 duoprism
・ 3-4 duoprism
・ 3-4-6-12 tiling
・ 3-5-8
・ 3-6 duoprism
・ 3-6-3 Rule
・ 3-7 kisrhombille
・ 3-7-77
・ 3-8 duoprism
・ 3-Acetyl-6-methoxybenzaldehyde
・ 3-Acetyloxymorphone
・ 3-aci-nitropropanoate oxidase
・ 3-Alkylpyridinium
・ 3-Allylfentanyl
・ 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate—CoA ligase
3-alpha-HSD
・ 3-Amino-1,2,4-triazole
・ 3-Amino-5-nitrosalicylic acid
・ 3-Amino-9-ethylcarbazole
・ 3-Aminoacridine
・ 3-Aminobenzamide
・ 3-Aminobenzoic acid
・ 3-aminobutyryl-CoA ammonia-lyase
・ 3-Aminoisobutyric acid
・ 3-Aminophenol
・ 3-aminophthalate
・ 3-Aminopyridine
・ 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone
・ 3-Azidocoumarin
・ 3-Benzhydrylmorpholine


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3-alpha-HSD : ウィキペディア英語版
3-alpha-HSD

3α-hydroxysteroid dehydrogenase (3α-HSD), also known as aldo-keto reductase family 1 member C4, is an enzyme that in humans is encoded by the ''AKR1C4'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1109 )〕 It is known to be necessary for the synthesis of the endogenous neurosteroids allopregnanolone, THDOC, and 3α-androstanediol. It is also known to catalyze the reversible conversion of 3α-androstanediol (5α-androstane-3α,17β-diol) to dihydrotestosterone (DHT) (5α-androstan-17β-ol-3-one) and vice versa.
== Function ==

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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