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3-methoxytyramine : ウィキペディア英語版
3-Methoxytyramine

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3-Methoxytyramine (3-MT), also known as 3-methoxy-4-hydroxyphenethylamine, is a metabolite of the neurotransmitter dopamine formed by the introduction of a methyl group to dopamine by the enzyme catechol-O-methyl transferase (COMT). 3-MT can be further metabolized by the enzyme monoamine oxidase (MAO) to form homovanillic acid (HVA), which is then typically excreted in the urine.
Originally thought to be physiologically inactive, 3-MT has recently been shown to act as an agonist of human TAAR1.
== Occurrence ==
3-Methoxytyramine occurs naturally in the prickly pear cactus (genus ''Opuntia''),〔 Retrieved on June 12, 2009 through Google Book Search.〕 and is in general widespread throughout the Cactaceae.〔T. A. Smith (1977). "Phenethylamine and related compounds in plants." ''Phytochem.'' 16 9-18.〕 It has also been found in crown gall tumors on ''Nicotiana'' sp.〔S. D. Mitchell, J. L. Firmin and D. O. Gray (1984). "Enhanced 3-methoxytyramine levels in crown gall tumours and other undifferentiated plant tissues." ''Biochem J.'' 221 891-5.〕

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