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3-monoacetylmorphine : ウィキペディア英語版
3-Monoacetylmorphine

3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine), the other two being morphine and more active 6-monoacetylmorphine (6-MAM).
Because of the acetyl-group in 3-position, 3-MAM has relatively weak affinity to μ-opioid receptors.
As ''3-O-acetylmorphine-6-O-sulfate'' (C19H23NO7S), where 6-OH is changed to 6-O-SO3, it can act as potent, centrally acting morphine derivative and has important analgesic properties. 〔(3-O-Acetylmorphine-6-O-sulfate: A potent, centrally acting morphine derivative )〕 〔(3-O-Acetylmorphine-6-O-sulfate )〕 〔(Dihydromorphine-6-''O''-sulfate )〕
==References==



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