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3β-Dihydroprogesterone
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3β-Dihydroprogesterone : ウィキペディア英語版
3β-Dihydroprogesterone

3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxy-4-pregnen-20-one, is an endogenous steroid. It is biosynthesized by 3β-hydroxysteroid dehydrogenase from progesterone. Unlike 3α-dihydroprogesterone, 3β-DHP does not act as a positive allosteric modulator of the GABAA,〔 which is in accordance with the fact that other 3β-hydroxylated progesterone metabolites such as isopregnanolone and epipregnanolone similarly do not act as potentiators of this receptor and instead inhibit it as well as reverse the effects of potentiators like allopregnanolone.
==See also==

* 5α-Dihydroprogesterone
* 5β-Dihydroprogesterone
* 3β-Androstanediol

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「3β-Dihydroprogesterone」の詳細全文を読む



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