|
|Section2= |Section3= }} 4,4'-Dihydroxybenzophenone is an organic compound with the formula (HOC6H4)2CO. This off-white solid is a precursor to or a degradation product of diverse commercial materials. It is a potential endocrine disruptor.〔Eddine, Ali Nasser; von Kries, Jens P.; Podust, Mikhail V.; Warrier, Thulasi; Kaufmann, Stefan H. E.; Podust, Larissa M. "X-ray Structure of 4, 4 '- Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14a -Demethylase (CYP51)" Journal of Biological Chemistry (2008), 283, pp. 15152-15159. 〕 == Synthesis == 4,4'-Dihydroxybenzophenone is prepared by the rearrangement of ''p''-hydroxyphenylbenzoate: :HOC6H4CO2C6H5 → (HOC6H4)2CO Alternatively, ''p''-hydroxybenzoic acid can be converted to ''p''-acetoxybenzoyl chloride. This acid chloride reacts with phenol to give, after deacetylation, 4,4'-dihydroxybenzophenone. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「4,4'-Dihydroxybenzophenone」の詳細全文を読む スポンサード リンク
|