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4-Androstenediol : ウィキペディア英語版 | 4-Androstenediol
|Section2= |Section3= }} Δ4-Androstenediol is an androstenediol that is converted to testosterone. The conversion rate is about 15.76%, almost triple that of Δ4-androstenedione, due to utilization of a different enzymatic pathway. There is also some conversion into estrogen, since testosterone is the metabolic precursor of the estrogens. Δ4-Androstenediol is closer to testosterone structurally than Δ5-androstenediol, and has androgenic effects, acting as a weak partial agonist of the androgen receptor. However, due to its lower intrinsic activity in comparison, in the presence of full agonists like testosterone or dihydrotestosterone (DHT), Δ4-androstenediol has antagonistic actions, behaving more like an antiandrogen.〔 ==Medical and commercial use== Patrick Arnold holds a 1999 patent on "Use of 4-androstenediol to increase testosterone levels in humans".〔http://www.patentstorm.us/patents/5880117/description.html〕
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