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4-fluoro-5-methoxy-DMT : ウィキペディア英語版 | 4-Fluoro-5-methoxy-DMT
4-Fluoro-5-Methoxy-''N'',''N''-dimethyltryptamine (4-F-5-MeO-DMT) was first described by David E. Nichols team in 2000. It is a potent 5-HT1A agonist. Substitution with the 4-fluorine markedly increased 5-HT1A selectivity over 5-HT2A/2C receptors with potency greater than that of the 5-HT1A agonist 8-OH-DPAT. The analog compound with the ''N'',''N''-dialkyl substituents constrained into a pyrrolidine ring, is a slightly stronger agonist for the 5-HT1A receptor and retains the selectivity over the 5-HT2A/2C receptors. == See also ==
* 5-Fluoro-AMT * 6-Fluoro-DMT
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