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5'-Guanidinonaltrindole : ウィキペディア英語版 | 5'-Guanidinonaltrindole
5'-Guanidinonaltrindole (5'-GNTI) is an opioid antagonist used in scientific research which is highly selective for the κ opioid receptor. It is 5x more potent and 500 times more selective than the commonly used κ-opioid antagonist norbinaltorphimine. It has a slow onset and long duration of action, and produces antidepressant effects in animal studies. It also increases allodynia by interfering with the action of the κ-opioid peptide dynorphin. ==See also==
* 6'-Guanidinonaltrindole * Binaltorphimine * JDTic
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「5'-Guanidinonaltrindole」の詳細全文を読む
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