翻訳と辞書 Words near each other ・ 5-3-2 ・ 5-4-3 rule ・ 5-4-3-2-Run ・ 5-5 duoprism ・ 5-7-9 ・ 5-alpha reductase ・ 5-alpha-reductase deficiency ・ 5-alpha-reductase inhibitor ・ 5-amino-6-(5-phosphoribosylamino)uracil reductase ・ 5-Aminoimidazole ribotide ・ 5-aminopentanamidase ・ 5-aminovalerate transaminase ・ 5-Androstenediol ・ 5-Androstenedione ・ 5-APB ・ 5-APDB ・ 5-APDI ・ 5-Benzyloxytryptamine ・ 5-beta-reductase ・ 5-Bromo-4-chloro-3-indolyl phosphate ・ 5-Bromo-DMT ・ 5-Bromouracil ・ 5-Bromouridine ・ 5-Carboxamidotryptamine ・ 5-carboxymethyl-2-hydroxymuconate Delta-isomerase ・ 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase ・ 5-cell ・ 5-cell honeycomb ・ 5-centimeter band ・ 5-Chloro-αMT Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク 5-APDB ： ウィキペディア英語版 5-APDB 5-(2-Aminopropyl)-2,3-dihydrobenzofuran (5-APDB, 3-Desoxy-MDA, EMA-4) is a putative entactogen drug of the phenethylamine and amphetamine classes. It is an analogue of MDA where the heterocyclic 3-position oxygen from the 3,4-methylenedioxy ring has been replaced by a methylene bridge.〔 6-APDB is an analogue of 5-APDB where the 4-position oxygen has been replaced by a methylene bridge instead.〔 5-APDB was developed by a team led by David E. Nichols at Purdue University as part of their research into non-neurotoxic analogues of MDMA.〔 In animal studies, 5-APDB's effects generalize most closely to non-stimulant MDMA analogues such as MBDB and MMAI, while producing no substitution for LSD or amphetamine.〔 ''In vitro'' studies show that 5-APDB acts as a highly selective serotonin releasing agent (SSRA), with IC50 values of 130 nM, 7,089 nM, and 3,238 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively.〔 In contrast, 6-APDB is more balanced on the three monoamine neurotransmitters and acts more similarly to MDA and MDMA.〔 Anecdotal reports from human users suggest that 5-APDB produces mild empathy but with relatively little euphoria and is accompanied by sedation. Methoxy-substituted analogues of 5-APDB and 6-APDB have also been made and substituted for DOM in animal tests, although they were around 10x less potent than DOM. ==Legal Status== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「5-APDB」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.