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5-Methoxy-2,N,N-trimethyltryptamine : ウィキペディア英語版 | 5-MeO-2-TMT
5-Methoxy-2,''N'',''N''-trimethyltryptamine (5-MeO-2,''N'',''N''-TMT, 5-MeO-TMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic. It was first synthesized by Alexander Shulgin and reported in his book TiHKAL ("Tryptamines i Have Known And Loved").〔(Erowid Online Books : "TIHKAL" - #45 5-MEO-TMT )〕 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75-150 mg orally, but these are relatively mild compared to those of other similar compounds. This suggests that while the methyl group on the 2-position of the molecule has impaired the binding of metabolic enzymes like monoamine oxidase (MAO), it is also interfering with binding to and/or activation of the serotonin 5-HT2A receptor, the target responsible for mediating the hallucinogenic effects of such compounds. == See also ==
* 2,''N'',''N''-Trimethyltryptamine (2,''N'',''N''-TMT) * 5-MeO-7-TMT
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