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5-Methyl-3,4-methylenedioxyamphetamine (5-Methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class. It is a ring-methylated derivative of MDA and a structural isomer of MDMA. Drug discrimination studies showed that 5-methyl-MDA substitutes for MDA, MMAI, and LSD, but not amphetamine, suggesting that it produces a mix of entactogen and hallucinogenic effects without any stimulant effects. 5-Methyl-MDA acts as a selective serotonin releasing agent (SSRA) with IC50 values of 107nM, 11,600nM, and 1,494nM for serotonin, dopamine, and norepinephrine efflux.〔 It is over 5x more potent than MDA, with a suitable active dose possibly being around 15–25 mg.〔〔 Subsequent testing, however, has found that it is not as potent as once thought and is active at at least 100mg. 2-Methyl-MDA is also much more potent than MDA, but is not quite as potent as 5-methyl-MDA.〔 6-methyl-MDMA (also known as Madam-6) is mostly inactive, likely due to steric hindrance.〔〔(PIHKAL #98 )〕 Recent research has used data on 2-methyl-MDA and 5-methyl-MDA to help guide computer modeling of the serotonin transporter complex. The synthesis of 5-methyl-MDA can be found online.〔 == See also == * 2-Methyl-MDA * 6-Methyl-MDA * EDA * MMDA 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「5-Methyl-MDA」の詳細全文を読む スポンサード リンク
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