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6β-Naltrexol-d4
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6β-Naltrexol-d4 : ウィキペディア英語版
6β-Naltrexol-d4

6β-Naltrexol-d4, also known as 6β-hydroxynaltrexone-d4, is a deuterium-labeled form of 6β-naltrexol used for NMR imaging. Unlike opioid inverse agonists such as naloxone and naltrexone (which are often dubbed "antagonists" for simplicity's sake), 6β-naltrexol and 6β-naltrexol-d4 are opioid neutral antagonists.〔(The Relative Potency of Inverse Opioid Agonists and a Neutral Opioid Antagonist in Precipitated Withdrawal and Antagonism of Analgesia and Toxicity. ) Sunil Sirohi, Shveta V. Dighe, Priyanka A. Madia and Byron C. Yoburn〕
==References==




抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「6β-Naltrexol-d4」の詳細全文を読む



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