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Methoxsalen
Methoxsalen — also called xanthotoxin, marketed under the trade names ''Oxsoralen'', ''Deltasoralen'', ''Meladinine'' — is a drug used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to UVA light from lamps or sunlight. Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly clearing up the disease. The dosage comes in 10 mg tablets, which are taken in the amount of 30 mg 75 minutes before a PUVA (psoralen + UVA) light treatment.
Chemically, methoxsalen belongs to a class of organic natural molecules known as furanocoumarins. They consist of coumarin annulated with furan. It can also be injected and used topically.
== Natural occurrences ==
Methoxsalen is extracted from ''Ammi majus'', a plant of the family Apiaceae. The substance is also present in other Apiaceae as well as Rutaceae, for example bergamot oil which is used in many perfumes and aromatherapy oils. When these products are applied to skin and exposed to UVA radiation, the skin may turn brownish due to the phototoxic effects of methoxsalen present in the bergamot oil.〔(【引用サイトリンク】 url=http://www.oilsandplants.com/bergamot.htm )〕 Most modern perfumes containing bergamot have the Methoxsalen removed.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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