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・ 8-inch Gun M1
・ 8-inch Howitzer
・ 8-inch M1888
・ 8-inch Mk. VI railway gun
・ 8-Lug HD Truck magazine
・ 8-Methoxymethyl-3-isobutyl-1-methylxanthine
・ 8-N-1
・ 8-OH-DPAT
・ 8-OH-PBZI
・ 8-orthoplex
・ 8-Oxo-2'-deoxyguanosine
・ 8-oxo-dGDP phosphatase
・ 8-oxo-dGTP diphosphatase
・ 8-oxocoformycin reductase
・ 8-Oxogeranial
8-Oxoguanine
・ 8-oxoguanine deaminase
・ 8-pallo
・ 8-Pass Charlie
・ 8-Phenyltheophylline
・ 8-pounder long gun
・ 8-Prenylnaringenin
・ 8-simplex
・ 8-simplex honeycomb
・ 8-track
・ 8-Track Flashback
・ 8-track tape
・ 8-way
・ 8-Way Santa
・ 8-y km


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8-Oxoguanine : ウィキペディア英語版
8-Oxoguanine

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8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species and can result in a mismatched pairing with Adenine resulting in G to T and C to A substitutions in the genome. In humans, it is primarily repaired by the DNA glycosylase OGG1. It can be caused by ionizing radiation, in connection with oxidative metabolism.

== 8- Oxoguanine in Body fluids==

Increased concentrations of 8-oxoguanine in body fluids have been found to be associated with increased risk of mutagenesis and carcinogenesis.
Care must be taken in the assay of 8-oxoguanine due to the ease with which it can be oxidised during extraction and the assay procedure.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「8-Oxoguanine」の詳細全文を読む



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