翻訳と辞書 Words near each other ・ 90th New York State Legislature ・ 90th New York Volunteer Infantry Regiment ・ 90th Ohio Infantry ・ 90th Operations Group ・ 90th parallel ・ 90th Pennsylvania Infantry ・ 90th Punjabis ・ 90th Regiment ・ 90th Regiment of Foot (disambiguation) ・ 90th Regiment of Foot (Perthshire Volunteers) ・ 90th Street ・ 90th Street – Elmhurst Avenue (IRT Flushing Line) ・ 90th Troop Carrier Squadron ・ 90th Troop Command ・ 90th United States Congress ・ 90Y-DOTA-biotin ・ 91 ・ 91 (disambiguation) ・ 91 (number) ・ 91 Aegina ・ 91 Aquarii ・ 91 Aquarii b ・ 91 B-Line ・ 91 BC ・ 91 Line ・ 91 Street, Edmonton ・ 91 Wireless ・ 91.1 FM ・ 91.2 FM ・ 91.3 Capital FM Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク 90Y-DOTA-biotin ： ウィキペディア英語版 90Y-DOTA-biotin 90Y-DOTA-biotin consists of a radioactive substance (yttrium-90) complexed by a chelating agent (DOTA), which in turn is attached to the vitamin biotin via a chemical linker. It is used experimentally in pretargeted radioimmunotherapy. Animal studies have been conducted〔〔 as well as clinical studies in humans.〔〔 In pretargeted radioimmunotherapy, two or three medications are applied in succession. At first, an antibody-drug conjugate is administered, which consists of a monoclonal antibody designed to target the tumour, and a chemical marker which in the case of DOTA-biotin therapy is one of the proteins avidin and streptavidin. After a time of typically one or two days to let the antibody accumulate in the tumour, a clearing agent may be given to eliminate residues of antibody that are still circulating in the bloodstream; this is especially done in humans. After a further waiting time, the radiotherapy (90Y-DOTA-biotin) is administered. Due to the high affinity of biotin to avidin and streptavidin, the radiotherapy accumulates where the antibody is, namely in the tumour, where it delivers its radioactivity.〔 == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「90Y-DOTA-biotin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.