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ADBICA
ADBICA (also known as ADB-PICA) is a designer drug identified in synthetic cannabis blends in Japan in 2013. ADBICA had not previously been reported in the scientific literature prior to its sale as a component of synthetic cannabis blends. ADBICA features a carboxamide group at the 3-indole position, like SDB-001 and STS-135. The stereochemistry of the tert-butyl side-chain in the illicitly sold product is unresolved, though in a large series of indazole derivatives structurally similar to ADBICA that are disclosed in Pfizer patent WO 2009/106980, activity resides exclusively in the (S) enantiomers.〔(Buchler IP et al, INDAZOLE DERIVATIVES. WO 2009/106980 )〕 ADBICA is a potent agonist of the CB1 receptor and CB2 receptor with a EC50 value of 0.69 nM and 1.8 nM respectively. ==Legal Status==
As of October 2015 ADBICA is a controlled substance in China.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ADBICA」の詳細全文を読む
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