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ADME-Tox : ウィキペディア英語版
ADME
ADME is an abbreviation in pharmacokinetics and pharmacology for "absorption, distribution, metabolism, and excretion," and describes the disposition of a pharmaceutical compound within an organism. The four criteria all influence the drug levels and kinetics of drug exposure to the tissues and hence influence the performance and pharmacological activity of the compound as a drug.
The abbreviation LADME is seen sometimes -- the L stands for "liberation" and deals with details of the route of administration such as what a tablet will do at a given gastric pH level, the creation of extended-release injectables for IM or SC use and the like.〔Inside Narcotics, 6th Edition (2014) pp 467 "Glossary"〕
== Components ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「ADME」の詳細全文を読む



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