翻訳と辞書 Words near each other ・ Aedoeus brevicollis ・ Aedoeus concolor ・ Aedoeus geniculatus ・ Aedoeus marginatus ・ Aedoeus thoracicus ・ Aedophron ・ Aedophron phlebophora ・ Aedophron rhodites ・ Aedophron sumorita ・ Aedophron venosa ・ Aedui ・ Aedulla ・ Aedy Ashraf ・ AEE ・ AEE UAV ・ AEE788 ・ AEEB Coach of the Year Award ・ AEECL's sportive lemur ・ AEF ・ AEF Monotrace ・ Aefgen Listincx ・ Aefligen ・ AEG ・ AEG (disambiguation) ・ AEG B.I ・ AEG B.II ・ AEG B.III ・ AEG C.I ・ AEG C.II ・ AEG C.III Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク AEE788 ： ウィキペディア英語版 AEE788 AEE788 is a multitargeted human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2 receptor family tyrosine kinases inhibitor with IC50 of 2, 6, 77, 59 nM for EGFR, ErbB2, KDR, and Flt-1. In cells, growth factor-induced EGFR and ErbB2 phosphorylation was also efficiently inhibited with IC50s of 11 and 220 nM, respectively. It efficiently inhibited growth factor-induced EGFR and ErbB2 phosphorylation in tumors for >72 h, a phenomenon correlating with the antitumor efficacy of intermittent treatment schedules. It also inhibits VEGF-induced angiogenesis in a murine implant model. It has potential as an anticancer agent targeting deregulated tumor cell proliferation as well as angiogenic parameters. == The IC50 value of AEE788 against of different kinases == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「AEE788」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.