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・ Akashdeep Saigal
・ Akashe Ki Ranga Lagila
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・ Akashi
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・ Akashi Castle
・ Akashi Domain
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・ AKAP1
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AKAP12
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・ AKAP6
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・ AKAP8
・ AKAP8L
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・ Akaparambu
・ Akapei Latu
・ Akapnou
・ Akapo Emmanuel


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AKAP12 : ウィキペディア英語版
AKAP12

A-kinase anchor protein 12 is an enzyme that in humans is encoded by the ''AKAP12'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9590 )
== Function ==

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「AKAP12」の詳細全文を読む



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