翻訳と辞書 Words near each other ・ Akashe Ki Ranga Lagila ・ Akasher Street-e Hante Digital Narod ・ Akashi ・ Akashi (surname) ・ Akashi Castle ・ Akashi Domain ・ Akashi Kaikyō Bridge ・ Akashi Kakuichi ・ Akashi Morishige ・ Akashi Motojiro ・ Akashi Park Stadium ・ AKAP1 ・ AKAP10 ・ AKAP11 ・ AKAP12 ・ AKAP13 ・ AKAP2 ・ AKAP3 ・ AKAP4 ・ AKAP5 ・ AKAP6 ・ AKAP7 ・ AKAP8 ・ AKAP8L ・ AKAP9 ・ Akaparambu ・ Akapei Latu ・ Akapnou ・ Akapo Emmanuel ・ Akapol Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク AKAP13 ： ウィキペディア英語版 AKAP13 A-kinase anchor protein 13 is an enzyme that in humans is encoded by the ''AKAP13'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11214 )〕 == Function == The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP-binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and, in addition, function as protein kinase A-anchoring proteins.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11214 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「AKAP13」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.