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ALK-Abelló
ALK-Abelló (), also commonly known as ALK, is a Denmark-based pharmaceutical company which specializes in the development and manufacture of allergy immunotherapy (AIT) products for the prevention and treatment of allergy. It is the world’s largest maker of allergy immunotherapy products (also known as ‘allergy vaccines’)〔(【引用サイトリンク】title=Stallergenes Annual Report 2012 )〕 with 76% of its revenue coming from sales in Europe.〔
==History==
ALK-Abello dates back to 1923〔 when Denmark’s first allergen extracts were produced at the pharmacy of the Copenhagen University Hospital.〔(【引用サイトリンク】title=Jacobsen K. "From Goose Feathers to Grazax- The History of ALK" )〕 The company was established as Allergologisk Laboratorium København by Dr. Barfod in 1928. The company has since focused on mapping the mechanisms of allergic impact on the immune system in order to develop new and improved allergy therapies. The research focuses on prevention, treatment, and management of allergies, especially hay fever and asthma.
In 1978, ALK released the first standardized line of products for the treatment of allergies. In the 1990s, ALK was the first company to launch sublingual immunotherapy drops (allergy immunotherapy administered as droplets under the tongue). In recent years, ALK’s research and development strategy has been focused on introducing a range of sublingual immunotherapy tablets (SLIT-tablets). The first, Grazax, was launched in 2006, becoming the first SLIT-tablets to be proven effective in the treatment of hay fever, or more specifically “showing a disease-modifying effect on grass pollen-induced allergic rhinoconjunctivitis.”〔Senna GE, Calderon M, Milani M. “Allergy Immunotherapy Tablet: Grazax for the treatment of grass pollen allergy". Expert Rev Clinical Immunology. 2011. Jan 7 (1).〕 A SLIT-tablet for ragweed allergy was launched in 2014. The company is part-owned by the Lundbeck Foundation, however is also a publicly traded entity.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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