翻訳と辞書 Words near each other ・ Amadalli ・ Amadan Dubh ・ Amadapur ・ Amadas ・ Amadas (disambiguation) ・ Amadas Coach ・ Amade ・ Amade Camal ・ Amadea Duraković ・ Amadea Palaiologina of Montferrat ・ AM-6545 ・ AM-679 ・ AM-679 (cannabinoid) ・ AM-679 (FLAP inhibitor) ・ AM-69 Georges Payre ・ AM-694 ・ AM-855 ・ AM-905 ・ AM-906 ・ AM-919 ・ AM-938 ・ AM-Franc ・ Am-heh ・ AM-Lira ・ AM-Mark ・ Am-Pol Eagle Citizen of the Year Award ・ AM/FM/GIS ・ AM1 ・ AM1* ・ AM1200 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク AM-694 ： ウィキペディア英語版 AM-694 AM-694 (1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole) is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB1. It is used in scientific research for mapping the distribution of CB1 receptors. No public data about AM-694 metabolism is known. AM-694 has already emerged as a designer drug. ==Pharmacology== AM-694 is an agonist for cannabinoid receptors. Affinities are: with a Ki of 0.08nM at CB1 and 18x selectivity over CB2 with a Ki 1.44nM. It is unclear what is responsible for this unusually high CB1 binding affinity, but it makes the 18F radiolabelled derivative of AM-694 useful for mapping the distribution of CB1 receptors in the body.〔Willis PG, Katoch-Rouse R, Horti AG. Regioselective F-18 radiolabeling of AM694, a CB1 cannabinoid receptor ligand. ''Journal of Labelled Compounds and Radiopharmaceuticals'' 2003;46(9):799-804. 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「AM-694」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.