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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク AMPD3 ： ウィキペディア英語版 AMPD3 AMP deaminase 3 is an enzyme that in humans is encoded by the ''AMPD3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=272 )〕 ==Model organisms== Model organisms have been used in the study of AMPD3 function. A conditional knockout mouse line, called ''Ampd3tm2a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty eight tests were carried out on mutant mice and four significant abnormalities were observed.〔 Mutant animals had increased IgG1 levels, increased trabecular bone thickness, decreased B cell numbers / increased granulocyte number and unusual brain histopathology (the thickness of the stratum radiatum was reduced and the dorsal 3rd ventricle area was increased).〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「AMPD3」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.