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ANAPC1
Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ''ANAPC1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64682 )〕 ANAPC1 is one of at least ten subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle (supplied by OMIM).〔 ==Interactions== ANAPC1 has been shown to interact with ANAPC5, ANAPC4,〔〔 ANAPC2,〔〔 CDC27〔〔 and ANAPC7.〔〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ANAPC1」の詳細全文を読む
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