翻訳と辞書 Words near each other ・ Arfamoussaya ・ Arfan Akram ・ Arfan Bhatti ・ Arfan Nisho ・ Arfana Mallah ・ Arfanabad ・ Arfaptin ・ Arfara ・ ARFB ・ ARFC ・ Arfendazam ・ Arfersiorfik Fjord ・ Arfeuille-Châtain ・ Arfeuilles ・ Arff ・ ARFGAP1 ・ ARFGAP3 ・ ARFGEF1 ・ ARFGEF2 ・ Arfi Lamba ・ Arfiane El Bared ・ Arfin Rumey ・ ARFIP1 ・ ARFIP2 ・ Arflex ・ Arfon ・ Arfon (Assembly constituency) ・ Arfon (UK Parliament constituency) ・ Arfon by-election ・ Arfon by-election, 1911 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ARFGAP1 ： ウィキペディア英語版 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 is an enzyme that in humans is encoded by the ''ARFGAP1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55738 )〕 Two transcript variants encoding different isoforms have been found for this gene. == Function == The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinositides and inhibited by phosphatidylcholine.〔 The protein has two ALPS (amphipatic lipid packing sensor) motifs, that let the protein sense the curvature of the membrane (<30 nm) or lipid packing defects, and in this way evaluate if the vesicule is mature and ready for coat disassembly. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ARFGAP1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.