翻訳と辞書 Words near each other ・ Arhan, Iran ・ Arhangel ・ Arhansus ・ Arhat ・ Arhatha ・ Arhatic yoga ・ Arhavi ・ Arhavispor ・ Arhedi ・ ARHGAP1 ・ ArhGAP11B and human encephalisation ・ ARHGAP18 ・ ARHGAP19 ・ ARHGAP24 ・ ARHGAP25 ・ ARHGAP26 ・ ARHGAP29 ・ ARHGAP31 ・ ARHGAP4 ・ ARHGAP44 ・ ARHGAP5 ・ ARHGAP8 ・ ARHGAP9 ・ ARHGDIA ・ ARHGDIB ・ ARHGDIG ・ ARHGEF1 ・ ARHGEF10 ・ ARHGEF11 ・ ARHGEF12 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ARHGAP26 ： ウィキペディア英語版 ARHGAP26 Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ''ARHGAP26'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23092 )〕 == Function == GRAF1 is a multidomain protein that is necessary for the CLIC/GEEC endocytic pathway. By virtue of an N-terminal BAR domain, GRAF1 sculpts the endocytic membranes of this pathway into 40 nm diameter tubules and vesicles that allow uptake of extracellular fluid, GPI-linked proteins and certain bacterial exotoxins into cells. The role of dynamin in the CLIC/GEEC pathway is controversial, but GRAF1 interacts strongly with this protein and acute inhibition of dynamin action abrogates CLIC/GEEC endocytosis. There are several members of the GRAF family of proteins, including GRAF2, GRAF3, and oligophrenin, all of which likely playing similar roles during clathrin-independent endocytic events. Mutations of both GRAF1 and oligophrenin are strongly implicated in causing human disease (leukaemia and mental retardation, respectively). Recently, autoantibodies to ARHGAP26 have been implicated in autoimmune cerebellar ataxia. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ARHGAP26」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.