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・ Arid
・ Arid (band)
・ Arid Diagonal
・ ARID domain
・ Arid Forest Research Institute
・ Arid Garcia
・ Arid Lands Ecology Reserve
・ Arid Lands Information Network
・ Arid thicket rat
・ Arid Uka
・ ARID1A
・ ARID1B
・ ARID2
・ ARID3A
・ ARID3B
ARID4A
・ ARID4B
・ ARID5B
・ Arida
・ Arida (plant)
・ Arida arizonica
・ Arida Border Crossing
・ Arida District, Wakayama
・ Arida, Wakayama
・ Aridaea
・ Aridaeus thoracicus
・ Aridagawa, Wakayama
・ Aridagricola
・ Aridane Santana
・ Aridani Arbelo


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ARID4A : ウィキペディア英語版
ARID4A

AT rich interactive domain 4A (RBP1-like), also known as ARID4A, is a protein which in humans is encoded by the ''ARID4A'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5926 )
== Function ==
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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