翻訳と辞書 Words near each other ・ AT-3 ・ AT-4 ・ AT-43 ・ AT-5 ・ AT-6 ・ AT-7 ・ AT-8 ・ AT-8 (Cuban mine) ・ AT-84 ・ AT-88 ・ AT-9 ・ At-Bashi ・ At-Bashi District ・ At-Bashi River ・ At-Bristol ・ AT-hook ・ AT-L ・ At-large ・ At-Large Advisory Committee ・ At-large bid ・ At-location mapping ・ At-risk students ・ AT-T ・ At-Ta'i ・ At-Tabaqa ・ At-Tabib (magazine) ・ At-Taghabun ・ At-Tahrim ・ At-Takathur ・ At-Takwir Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク AT-hook ： ウィキペディア英語版 AT-hook The AT-hook is a DNA-binding motif present in many proteins, including the high mobility group (HMG) proteins, DNA-binding proteins from plants and hBRG1 protein, a central ATPase of the human switching/sucrose non-fermenting (SWI/SNF) remodeling complex. This motif consists of a conserved, palindromic, core sequence of proline-arginine-glycine-arginine-proline, although some AT-hooks contain only a single proline in the core sequence. AT-hooks also include a variable number of positively charged lysine and arginine residues on either side of the core sequence. The AT-hook binds to the minor groove of adenine-thymine (AT) rich DNA, hence the AT in the name. The rest of the name derives from a predicted asparagine/aspartate "hook" in the earliest AT-hooks reported in 1990. In 1997 structural studies using NMR determined that a DNA-bound AT-hook adopted a crescent or hook shape around the minor groove of a target DNA strand (pictured at right). HMGA proteins contain three AT-hooks, although some proteins contain as many as 30.〔 The optimal binding sequences for AT-hook proteins are repeats of the form (ATAA)n or (TATT)n, although the optimal binding sequences for the core sequence of the AT-hook are AAAT and AATT. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「AT-hook」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.