翻訳と辞書 Words near each other ・ Athanas ・ Atez ・ Atezolizumab ・ Ateş ・ Ateş (newspaper) ・ Ateş hırsızı ・ Ateş Çınar ・ Ateşan Aybars ・ Ateşten Gömlek ・ ATF ・ ATF (video game) ・ ATF Dingo ・ ATF fictional sting operations ・ ATF gunwalking scandal ・ ATF/CREB ・ ATF1 ・ ATF3 ・ ATF4 ・ ATF5 ・ ATF6 ・ ATF7 ・ ATF7IP ・ Atfalati ・ ATFC ・ ATFE ・ Atfih ・ ATFQ ・ ATFS ・ ATG ・ ATG Javelin Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ATF1 ： ウィキペディア英語版 ATF1 Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ''ATF1'' gene. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.〔 == Clinical significance == Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=466 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ATF1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.