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・ ATP6V1B1
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・ ATP6V1D
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ATP6V1G3
・ ATP6V1H
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・ Atpara Upazila
・ ATPase
・ ATPase ASNA1
・ ATPase assay
・ ATPase, H+ transporting, lysosomal V0 subunit a1
・ ATPase, Na+/K+ transporting, alpha 1
・ ATPC RNA motif


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ATP6V1G3 : ウィキペディア英語版
ATP6V1G3

V-type proton ATPase subunit G 3 is an enzyme that in humans is encoded by the ''ATP6V1G3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=127124 )
== Function ==

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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