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・ Axillary fascia
・ Axillary lines
・ Axillary lymph nodes
・ Axillary lymphadenopathy
・ Axillary nerve
・ Axillary nerve dysfunction
・ Axillary nerve palsy
・ Axillary sheath
・ Axillary space
・ Axillary vein
・ Axillary wrasse
・ Axilrod–Teller potential
・ Axilspot hogfish
・ Axim
・ Axim X50 series
AXIN1
・ AXIN2
・ Axinaea
・ Axinaea merianiae
・ Axinaea nitida
・ Axinaea pauciflora
・ Axinaea quitensis
・ Axinaea sclerophylla
・ Axinaea sessilifolia
・ Axinaea sodiroi
・ Axinandra
・ Axinandra zeylanica
・ Axinella
・ Axinellidae
・ Axinidris


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AXIN1 : ウィキペディア英語版
AXIN1

Axin-1 is a protein that in humans is encoded by the ''AXIN1'' gene.
== Function ==

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8312 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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