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Aerobactin
|Section2= |Section3= }} Aerobactin is a bacterial iron chelating agent (siderophore) found in ''E. coli''. It is a virulence factor enabling ''E. coli'' to sequester iron in iron-poor environments such as the urinary tract. Aerobactin is biosynthesized by the oxidation of lysine, catalyzed by the enzyme aerobactin synthase, which is then coupled to citric acid. The gene for this enzyme is found in the aerobactin operon, which is roughly 8 kilobases long and contains 5 or more genes in total. ''Yersinia pestis'' contains genes relating to aerobactin, but they have been inactivated by a frameshift mutation, thus ''Y. pestis'' is no longer able to synthesize aerobactin. == Other homologs ==
* Rhizobactin from ''Sinorhizobium'' * Alcaligin from ''Bordetella''〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Aerobactin」の詳細全文を読む
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