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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Afloqualone ： ウィキペディア英語版 Afloqualone Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku.〔US Patent 3966731 - 2-Fluoromethyl-3-o-tolyl-6-amino-4(3H)-quinazolinone〕 It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor ,〔Ochiai T, Ishida R. Pharmacological studies on 6-amino- 2-fluoromethyl- 3-(O-tolyl)- 4(3H)- quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Japanese Journal of Pharmacology. 1982 Jun;32(3):427-38.〕 and has had some clinical use, although it causes photosensitization as a side-effect that can cause skin problems such as dermatitis.〔Ishikawa T, Kamide R, Niimura M. Photoleukomelanodermatitis (Kobori) induced by afloqualone. Journal of Dermatology. 1994 Jun;21(6):430-3.〕 == See also == * Methaqualone * Diproqualone * Etaqualone * Methylmethaqualone * Mecloqualone * Mebroqualone * Cloroqualone * Nitromethaqualone 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Afloqualone」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.