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Albendazole
・ Albendazole monooxygenase
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Albendazole : ウィキペディア英語版
Albendazole


Albendazole, marketed as Albenza among others, is medication used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among others. It is taken by mouth.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/albendazole.html )

Common side effects include nausea, abdominal pains, and headaches. Potentially serious side effects include bone marrow suppression which usually improves on stopping the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk.〔 It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by a pregnant women.〔 Albendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.〔

Albendazole came into use in 1971. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. In many areas of the world the wholesale cost is between 0.01 and 0.06 USD per dose.〔(【引用サイトリンク】url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=ALB200T&s_year=2014&year=2014&str=200%20mg&desc=Albendazole&pack=new&frm=TAB-CAP&rte=PO&class_code2=06%2E1%2E1%2E&supplement=&class_name=%2806%2E1%2E1%2E%29Intestinal%20anthelminthics%3Cbr%3E )〕 In the United States, however, it is very expensive as of 2014 at about 50 USD per dose.〔
== Medical uses ==
It is effective first-line of treatment against:
* Flatworms
*
* Flukes/trematodes
*
*
* Fasciolosis
*
* Tapeworm/cestodes
*
*
* Cysticercosis
*
*
* Echinococcosis
* Nematodes
*
* Enterobiasis (pinworm infection)〔
*
* Trichuriasis (whipworm infection)〔
*
* Toxocariasis
*
* Ascariasis
*
* Hookworm infection
*
* Strongyloidiasis
*
* Trichostrongyliasis
*
* Capillariasis
*
* Cutaneous larva migrans (caused by ''Ancylostoma'')
*
* Filariasis
* Myiasis

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Albendazole」の詳細全文を読む



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